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Selected Papers

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1.  Gou, L.T.*, Lim, D.H.*, Ma, W.B.*, Aubol, B.E., Hao, Y.J., Wang, X., Zhao, J., Liang, Z.Y., Shao, C.W.,          Zhang, X., Meng, F., Li, H.R., Zhang, X.R., Xu, R.M., Li, D.S., Rosenfeld, M.G., Mellon, P.L., Adams,          J.A., Liu, M.F., and Fu, X.D.  (2020) Initiation of Parental Genome Reprogramming in Fertilized                   Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation.

     Cell 180(6), 1212-1227 (*co-first authors) PMID: 3216915

       * 한빛사 논문 소개 한빛사 인터뷰

2.  Na, D.K*, Lim, D.H.*, Hong, J.S., Lee, H.M., Cho, D.A., Yu, M.S., Shaker, B., Ren, J.,

     Lee, B.M., Song, J.G., Oh, Y.N., Lee, K.G., Oh, K.S., Lee, M.Y., Choi, M.S., Choi, H.S.,

     Kim, Y.H., Bui, J.M., Leem K.S., Kim, H.W., Lee, Y.S.#, and Gsponer J.# (2023)

     A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration. 

     Mol. Syst. Biol.  e11801 (*co-first authors) PMID: 37984409 

     * 한빛사 논문 소개

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3.  Lee, S.J.*, Kim, N.Y.*, Jang, D.G., Kim, H.K., Kim, J.I., Jeon, J.W., and Lim, D.H. (2023)

     Ecdysone-induced microRNA miR-276a-3p controls developmental growth by targeting the 

     insulin receptor in Drosophila.

     Insect Mol. Biol. 32(6):703-715 (*co-first authors) PMID: 37702106

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4.  Lim, D.H.*#, Choi, M.S.*, Jeon, J.W.*, and Lee, Y.S.# (2023)

     MicroRNA miR-252-5p regulates the Notch signaling pathway by targeting Rab6 in Drosophila

     wing development.

     Insect Sci.  30(5), 1431-1444 (*co-first authors / #co-corresponding authors) PMID: 36847222

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5.  Kim, C.J.*, Kim, H.H.*, Kim, H.K., Lee, S.J., Jang D.G., Kim, C.H., and Lim, D.H. (2023)

     MicroRNA miR-263b-5p regulates developmental growth and cell association by suppressing

     Laminin A in Drosophila
     Biology 12(8), 1096 (*co-first authors) PMID: 37626982

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2024 ~

in Preparation

in Preparation

Revision

31.  Jang, D.G.*, Kim, C.J.*, Shin, B.H.*, and Lim, D.H. (2024)

       The biological roles of microRNAs in Drosophila development.

       Insects 15(7):491 (*co-first authors)

       [Review paper]

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30.  Jayne, N.D., Liang, Z, Lim, D.H., Chen, P.B., Diaz, C, Arimoto, K.-I., Xia, L., Ren, B., Fu, X.-D.,

       and Zhang, D.-E. (2024)

        RUNX1 C-terminal Mutations Impair Blood Cell Differentiation by Perturbing Specific Enhancer

        -Pormoter Networks

       Blood Adv. 8(10):2410-2423 PMID: 38513139

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2021 - 2023

29.  Na, D.K*, Lim, D.H.*, Hong, J.S., Lee, H.M., Cho, D.A., Yu, M.S., Shaker, B., Ren, J.,

       Lee, B.M., Song, J.G., Oh, Y.N., Lee, K.G., Oh, K.S., Lee, M.Y., Choi, M.S., Choi, H.S.,

       Kim, Y.H., Bui, J.M., Leem K.S., Kim, H.W., Lee, Y.S.#, and Gsponer J.# (2023)

       A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration. 

       Mol. Syst. Biol.  e11801 (*co-first authors) PMID: 37984409

       * 한빛사 논문 소개

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28.  Kim, H.K., Kim, C.J., Jang, D.G., and Lim, D.H. (2023)

       MicroRNA miR-274-5p suppresses found-in-neurons associated with melanotic mass

       formation and development growth in Drosophila. 

       Insects 14(8), 709 PMID: 37623419

       Preprints - doi: 10.20944/preprints202306.0501.v1

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27.  Kim, C.J.*, Kim, H.H.*, Kim, H.K., Lee, S.J., Jang D.G., Kim, C.H., and Lim, D.H. (2023)

       MicroRNA miR-263b-5p regulates developmental growth and cell association by suppressing

       Laminin A in Drosophila

       Biology 12(8), 1096 (*co-first authors) PMID: 37626982

Graphical_Abstract.png

26.  Lee, S.J.*, Kim, N.Y.*, Jang, D.G., Kim, H.K., Kim, J.I., Jeon, J.W., and Lim, D.H. (2023)

       Ecdysone-induced microRNA miR-276a-3p controls developmental growth by targeting the 

       insulin receptor in Drosophila.

       Insect Mol. Biol. 32(6):703-715 (*co-first authors) PMID: 37702106

2021_Sojeong_Lee.jpg
2021_Nayeon_Kim.jpg
대지 1.png

25.  Lim, D.H.*#, Choi, M.S.*, Jeon, J.W.*, and Lee, Y.S.# (2023)

       MicroRNA miR-252-5p regulates the Notch signaling pathway by targeting Rab6 in Drosophila

       wing development.

       Insect Sci.  30(5), 1431-1444 (*co-first authors / #co-corresponding authors) PMID: 36847222

2021_JiWon_Jeon.jpg

24.  Jayne, N, Liu, M.D., Chen, B.S., Liang, Z.Y., Lim, D.H., Ren, B., Fu, X.D., Zhang, D.E. (2022)

       Pathogenic RUNX1 C-Terminal Truncation Mutations Contribute to Differentiation Block and

       Result in Unique Changes in Transcription and Chromatin Organization. 

       Blood 140(supplement 1), 996-997 DOI:10.1182/blood-2022-163838

23.  Chen, J.Y.*, Lim, D.H.*, Chen, L., Zhou, Y.L., Zhang, F.L., Shao, C.W., Zhang, X., Li, H.R., 

       Wang, D., Zhang, D.E., and Fu, X.D. (2022)

       Systematic Evaluation of Different R-loop Mapping Methods: Achieving Consensus, 

       Resolving Discrepancies and Uncovering Distinct Types of RNA:DNA Hybrids. 

       BioRxiv. DOI:10.1101/2022.02.18.480986 (*co-first authors)

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22.  Li, L.X., Luo, H.F., Lim, D.H., Han, L., Li, Y., Fu, X.D., and Qi, Y.J. (2021)

       Global profiling of RNA-chromatin interactions reveals co-regulatory gene expression

       networks in Arabidopsis

       Nature Plants. 7(10), 1364-1378 PMID:34650265

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2018 - 2020

21.  Hao, Y.J., Wang, D.P., Wu, S.H., Li, X., Shao, C.W., Zhang, P., Chen, J.Y., Lim, D.H., Fu, X.D., He, S.M., and Chen,

       R.S. (2020) Active Retrotransposons Help Maintain Pericentromeric Heterochromatin Required for Faithful Cell Division.

       Genome Res. 30(11), 1570-1582. PMID:33060173

20.  Lee, S.J., Hong, J.S., Lim, D.H., and Lee, Y.S. (2020) Roles for Drosophila Cap1 2’-O-ribose methyltransferase in the

       small RNA silencing pathway associated with Argonaute 2. Insect Biochem. Mol. Biol. 123, 103415. PMID: 32504809

19.  Lim, D.H.*, Lee, S.J.*, Chou, M.S., Han, J.Y., Seong, Y.M., Na, D.K., Kwon, Y.S., and Lee, Y.S. (2020) The conserved

       microRNA miR-8-3p coordinates the expression of V-ATPase subunits to regulate ecdysone biosynthesis for Drosophila

       metamorphosis. FASEB J. 34(5), 6449-6465 (*co-first authors). PMID: 32196731

18.  Gou, L.T.*, Lim, D.H.*, Ma, W.B.*, Aubol, B.E., Hao, Y.J., Wang, X., Zhao, J., Liang, Z.Y., Shao, C.W., Zhang, X., Meng,

       F., Li, H.R., Zhang, X.R., Xu, R.M., Li, D.S., Rosenfeld, M.G., Mellon, P.L., Adams, J.A., Liu, M.F., and Fu, X.D.  (2020)

       Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine

       Phosphorylation. Cell 180(6), 1212-1227 (*co-first authors). PMID: 3216915

       * 한빛사 논문 소개 한빛사 인터뷰

17.  Chen, J.Y., Lim, D.H., and Fu, X.D. (2020) Mechanistic Dissection of RNA Binding Proteins in Regulated Gene

       Expression at Chromatin Levels. Cold Spring Harb. Symp. Quant. Biol. 84, 55-66. PMID: 31900328

16.  Zhou, B., Li, X., Luo, D., Lim, D.H., Zhou, Y., and Fu, X.D. (2019). GRID-seq for comprehensive analysis of global RNA-

       chromatin interactions. Nature Protocols. 14(7), 2036-2068. PMID: 31175345

15.  Lim, D.H.*, Lee, S.*, Han, J.Y.*, Choi, M.S., Hong, J.S., and Lee, Y.S. (2019). MicroRNA miR-252 targets mbt to control

       the developmental growth of Drosophila. Insect Mol. Biol. 28(3), 444-454. (*co-first authors). PMID: 30582233

14.  Lim, D.H.*, Lee, S.*, Han, J.Y., Choi, M.S., Hong, J.S., Seong, Y., Kwon, Y.S., and Lee, Y.S. (2018). Ecdysone-

       responsive microRNA-252-5p controls the cell cycle by targeting Abi in Drosophila. FASEB J. 32(8), 4519-4533. (*co-

       first authors). PMID: 29543534

13.  Bao, X., Guo, X., Yin, M., Tariq, M., Lai, Y., Kanwal, S., Zhou, J., Li, N., Lv, Y., Pulido-Quetglas, C., Wang, X., Ji, L.,

       Khan, M.J., Zhu, X., Luo, Z., Shao, C., Lim, D.H., Liu, X., Li, N., Wang, W., He, M.H., Liu, Y.L., Ward, C., Wang, T. ,

       Zhang, G., Wang, D.Y., Yang, J.H., Chen, Y.W., Zhang, C.L., Jauch, R., Yang, Y.G., Wang, Y.M., Qin, B.M., Anko, M.L.,

       Hutchins, A.P., Sun, H., Wang, H.T., Fu, X.D., Zhang, B.L., and Esteban, M.A. (2018). Capturing the interactome of

       newly transcribed RNA. Nature Methods. 15(3), 213-220. PMID: 29431736

 

12.  Lim, J.H., Kim, D.J., Lee, D.E., Han, J.Y., Chung, J.H., Ahn, H.K., Lee, S.W., Lim, D.H., Lee, Y.S., Park, S.Y., and Ryu,

       H.M. (2015). Genome-wide microRNA expression profiling in placentas of fetuses with Down syndrome. Placenta.   

       36(3), 322-328.

11.  Seong, Y., Lim, D.H., Kim, A., Seo, J.H., Lee, Y.S., Song, H., and Kwon, Y.S. (2014). Global identification of target

       recognition and cleavage by the Microprocessor in human ES cells. Nucleic Acids Res. 42(20), 12806-12821.

10.  Lim, D.H., Oh, C.T., Han, S.J., and Lee, Y.S. (2014). Methods for studying the biological consequences of endo-siRNA

       deficiency in Drosophila melanogaster. Methods Mol. Biol. 1173, 51-58.

9.  Joo, J.Y., Lee, J., Ko, H.Y., Lee, Y.S., Lim, D.H., Kim, E.Y., Cho, S., Hong, K.S., Ko, J.J., Lee, S., Lee, Y.S., Choi, Y.S.,

     Lee, K.A., and Kim, S.H. (2014). Microinjection free delivery of miRNA inhibitor into zygotes. Sci. Rep. 4, 5417.

8.  Lim, D.H., Lee, L., Oh, C.T., Kim, N.H., Hwang, S., Han, S.J., and Lee, Y.S. (2013). Microarray analysis of Drosophila

     dicer-2 mutants reveals potential regulation of mitochondrial metabolism by endogenous siRNAs. J. Cell. Biochem.

     114(2), 418-427.

7.  Kwak, G.H., Lim, D.H., Han, J.Y., Lee, Y.S., and Kim, H.Y. (2012). Methionine sulfoxide reductase B3 protects from

     endoplasmic reticulum stress in Drosophila and in mammalian cells. Biochem. Biophys. Res. Commun. 420(1), 130-

     135.

6.  Lim, D.H., Han, J.Y., Kim, J.R., Lee, Y.S., and Kim, H.Y. (2012). Methionine sulfoxide reductase B in the endoplasmic

     reticulum is critical for stress resistance and aging in Drosophila. Biochem. Biophys. Res. Commun. 419(1), 20-26.

5.  Lim, D.H.*, Oh, C.T.*, Lee, L., Hong, J.S., Noh, S.H., Hwang, S., Kim, S., Han, S.J., and Lee, Y.S. (2011). The

     endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis.

     FEBS Lett. 585(19), 3079-3085. (*co-first authors)

4.  Cho, I.S., Kim, J., Seo, H.Y., Lim, D.H., Hong, J.S., Park, Y.H., Park, D.C., Hong, K.C., Whang, K.Y., and Lee, Y.S.

     (2010). Cloning and characterization of microRNAs from porcine skeletal muscle and adipose tissue. Mol. Biol. Rep.

     37(7), 3567-3574.

3.  Lee, Y.S., Pressman, S., Andress, A.P., Kim, K., White, J.L., Cassidy, J.J., Li, X., Lubell, K., Lim, D.H., Cho, I.S.,   

     Nakahara, K., Preall, J.B., Bellare, P., Sontheimer, E.J., and Carthew, R.W. (2009). Silencing by small RNAs is linked to 

     endosomal trafficking. Nature Cell Biology 11(9), 1150-1156.

2.  Cho, I.S., Kim, J., Lim, D.H., Ahn, H.C., Kim, H., Lee, K.B., and Lee, Y.S. (2008). Improved serum stability and           

     biophysical properties of siRNAs following chemical modifications. Biotechnol. Lett. 30(11), 1901-1908.

1.  Lim, D.H.*, Kim, J.*, Kim, S.U., Carthew, R.W., and Lee, Y.S. (2008).  Functional analysis of dicer-2 missense mutations       in the siRNA pathway of Drosophila. Biochem. Biophys. Res. Commun. 371(3), 525-530. (*co-first authors)

2008-2015

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